When it comes to an itinerary, Travel + Leisure readers want more than a string of photo opportunities — and the right tour operator makes all the difference in creating a trip of a lifetime versus one that simply checks off a list of sights. This year, our readers were especially drawn to companies that utilize local expertise and experience to thoughtfully design trips that will entertain as well as inspire. Every year for our World's Best Awards survey, T+L asks readers to weigh in on travel experiences around the globe — to share their opinions on the top hotels, resorts, cities, islands, cruise ships, spas, airlines, and more. Readers rated tour operators and safari outfitters based on their staff and guides, itineraries and destinations, activities, accommodations, food, and overall value. The top picks were noted for their deep knowledge of destinations and guides who "go the extra mile." One reader who has been traveling for more than five decades ...